Scientists from the College of Medicine at the Catholic University of Korea have pub-lished newest data on the M2-PK test from a multi-center study of colorectal cancer screening in the journal ‚Gut and Liver‘. The results from cancer expert Professor Yong Kim and his col-leagues confirm the exceptionally high capability of the M2-PK test, particularly in comparison to the immunological fecal occult blood test (iFOBT), to detect adenomas and colorectal cancer.
In their study Professor Kim and colleagues investigated the enzymatic biomarker M2-PK with volunteers in patient groups with 139 cases of colorectal cancer and 124 with adenoma, along with a population-based control group of 60 people, making a total of 323 subjects. The sensitivity of the M2-PK test was 92.8% for colorectal cancer and 69.4% for adenomas. In addition, they also compared the results of the M2-PK test with those of an immunological fecal occult blood test (iFOBT). This was clearly inferior to the M2-PK test. The iFOBT detected only 47.5% of the colon cancers and just 12.1% of the adenomas. Consequently, the M2-PK test detected twice as many colorectal cancer cases and nearly six times the number of adenomas than the immunological fecal occult blood test (iFOBT). These scientific results from the University of Korea categorically confirm the capability of the fecal M2-PK test for screening and early detection of colorectal cancer.
The fecal M2-PK test is available as a qualitative rapid test under the name ScheBo® M2-PK QuickTM and as a fully quantitative ELISA stool test.
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Source: Kim YC, et al., Gut and Liver, online December 5th, 2014; http://dx.doi.org/10.5009/gnl13457, www.gutnliver.org/.
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